Van Damme plays Luc Deveraux, a former Vietnam War soldier who, after being killed in combat, is brought back to life as part of the Universal Soldier program. Lundgren portrays Sgt. Andrew Scott, Deveraux’s former commanding officer, who was also killed in the same conflict. Both men are reanimated with no memory of their past lives and programmed to obey orders without question. However, as they begin to regain memories of their previous lives, a personal vendetta reignites between the two.

The plot intensifies as Deveraux attempts to break free from the government’s control, while Scott, who has become mentally unstable, embraces his violent tendencies and seeks revenge. Their conflict leads to explosive, hand-to-hand combat and shootouts, showcasing both Van Damme’s and Lundgren’s physical prowess.