The show follows the elite Section 20, a top-secret branch of the British Secret Intelligence Service (MI6), tasked with handling dangerous operations across the globe. The narrative focuses on two main characters: Michael Stonebridge (Philip Winchester), a British Special Forces operative, and Damien Scott (Sullivan Stapleton), a former U.S. Delta Force operative. Together, they form a dynamic duo that battles terrorist organizations, rogue operatives, and other global threats.

Each season takes the team to different international locations, where they engage in high-stakes missions, often involving hostage rescues, intelligence gathering, and complex combat operations. Along the way, Stonebridge and Scott form a deep bond as they face personal and professional challenges, all while dealing with relentless enemies and ever-present danger.

Known for its realistic portrayal of military tactics, intense action sequences, and strong character development, Strike Back delivers a thrilling blend of action and espionage. The series explores themes of loyalty, sacrifice, and the moral complexities of war, while keeping viewers engaged with its explosive firefights and fast-paced storytelling.