When an experimental wildlife transport crashes into the heart of Lagos, the city turns into a bloody maze of teeth and claws. Tigers, hyenas and apex predators tear the urban landscape, but the real monsters remain human.

Leading the counterattack is Jack “Rhino” Dalton (Dwayne Johnson), a former reconnaissance commander tormented by a failed covert mission. He is joined by Elijah Vance (Michael B. Jordan), an elite tracker raised in the African savannah, who intuits something much more calculated beneath the chaos. As biological weapons, corporate treachery and primal survival instincts collide, the team discovers that it’s not about a random outbreak, but an armed invasion designed by a private rebel company known as Black Prism.

With time running out, the streets invaded and nature claiming the concrete, Dalton and Vance must hunt down not only the unleashed beasts, but also the men who set them free. When survival becomes a war zone, instinct is the most lethal weapon.